Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL27980898 | 0.94 | ALOX15 (0.40) | SLC7A5KMT2AALOX15BLMPMP22 | |
| Histidine SCHEMBL27980643 | 0.93 | ALOX15 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1KMT2A | |
| Histidine SCHEMBL27597274 | 0.89 | ALOX15 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL23632728 | 0.87 | SLC7A5 (0.37) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL21173602 | 0.87 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL16335546 | 0.87 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL21196864 | 0.86 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL6534153 | 0.86 | BLM (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL17628714 | 0.86 | BLM (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1239320 | 0.84 | ANPEP (0.36) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011070-A | Compound with hypoglycemic effect, composition and application thereof | ADDA BIOTECH INC | 2014-08-27 | — | — | CN | claimed |
| CN-109180802-A | Compound, composition with hypoglycemic effect and application thereof | 爱德迪安（北京）生物技术有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-104011070-A | Compound with hypoglycemic effect, composition and application thereof | ADDA BIOTECH INC | 2014-08-27 | — | — | CN | disclosed |