Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 0.87 |
| ▸ | BRAF | P15056 | 2/20 | 0.67 |
| ▸ | RAF1 | P04049 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21174119 | 0.99 | FLT3 (0.85) | FLT3BRAFRAF1 | |
| SCHEMBL20434905 | 0.93 | FLT3 (1.00) | FLT3BRAFRAF1 | |
| SCHEMBL22505687 | 0.85 | FLT3 (0.85) | FLT3 | |
| SCHEMBL22505620 | 0.85 | FLT3 (0.69) | FLT3BRAFRAF1 | |
| SCHEMBL22505622 | 0.85 | FLT3 (0.69) | FLT3BRAF | |
| SCHEMBL13234456 | 0.84 | RAF1 (0.69) | FLT3BRAFRAF1 | |
| SCHEMBL22505578 | 0.83 | FLT3 (0.66) | FLT3BRAFRAF1 | |
| SCHEMBL19459348 | 0.81 | BRAF (0.78) | FLT3BRAF | |
| SCHEMBL6376965 | 0.81 | FLT3 (0.79) | FLT3 | |
| SCHEMBL22505582 | 0.81 | FLT3 (0.64) | FLT3BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513809-B9 | MEDICINAL COMPOSITION COMPRISING TIVOZANIB | KYOWA KIRIN CO LTD (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4000634-A1 | MEDICINAL COMPOSITION COMPRISING TIVOZANIB | Kyowa Kirin Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |
| EP-3513809-A1 | MEDICINAL COMPOSITION | Kyowa Hakko Kirin Co., Ltd. (JP) | 2019-07-24 | — | — | EP | disclosed |