Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21174660 | 0.84 | MAPT (0.64) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL17498825 | 0.82 | KDM4E (0.42) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16148365 | 0.82 | MAPT (0.70) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16147320 | 0.80 | MAPT (0.59) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16147763 | 0.80 | KIT (0.56) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16147139 | 0.79 | MAPT (0.58) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16148533 | 0.79 | MAPT (0.60) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16147567 | 0.79 | KDM4E (0.60) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16148195 | 0.77 | MAPT (0.59) | MAPTKDM4ETDP1L3MBTL1GPR55 | |
| SCHEMBL16148311 | 0.76 | CA2 (0.35) | MAPTKDM4ETDP1L3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3514147-A1 | STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY | University of Maryland, Baltimore (US) | 2019-07-24 | — | — | EP | disclosed |