Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 9/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177567 | 0.86 | KLKB1 (0.35) | KLKB1MAP4K1MMEL1 | |
| SCHEMBL19780407 | 0.80 | KLKB1 (0.42) | KLKB1S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL19779879 | 0.80 | KLKB1 (0.52) | KLKB1MAP4K1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21177781 | 0.78 | KLKB1 (0.36) | KLKB1S1PR1S1PR3TP53MAP4K1 | |
| SCHEMBL20531521 | 0.78 | KLKB1 (0.43) | KLKB1ALDH1A1MAPT | |
| SCHEMBL21177362 | 0.78 | KLKB1 (0.38) | KLKB1MAP4K1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21177169 | 0.78 | KLKB1 (0.51) | KLKB1MAP4K1 | |
| SCHEMBL17442513 | 0.78 | KLKB1 (0.49) | KLKB1MAP4K1 | |
| SCHEMBL21179410 | 0.77 | HSP90AB1 (0.42) | KLKB1L3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21177545 | 0.76 | KLKB1 (0.34) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |