Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177362 | 0.89 | KLKB1 (0.38) | KLKB1MAP4K1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21177327 | 0.89 | S1PR1 (0.37) | KLKB1S1PR1S1PR3ALDH1A1MAPT | |
| SCHEMBL19780407 | 0.84 | KLKB1 (0.42) | KLKB1S1PR1S1PR3MAPK1NPSR1 | |
| SCHEMBL21179351 | 0.82 | KLKB1 (0.51) | KLKB1MAP4K1 | |
| SCHEMBL21177161 | 0.81 | KLKB1 (0.42) | KLKB1MAP4K1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL21190192 | 0.78 | ALOX15 (0.37) | KLKB1S1PR1S1PR3ALDH1A1MAPT | |
| SCHEMBL21177545 | 0.78 | KLKB1 (0.34) | KLKB1MAP4K1 | |
| SCHEMBL21177320 | 0.78 | KLKB1 (0.33) | KLKB1MAP4K1 | |
| SCHEMBL21177142 | 0.78 | KLKB1 (0.36) | KLKB1S1PR1S1PR3MAP4K1ALDH1A1 | |
| SCHEMBL21177623 | 0.78 | KLKB1 (0.33) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |