Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177195 | 0.85 | KDM4E (0.35) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL22610172 | 0.85 | KDM4E (0.35) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL21179378 | 0.80 | CA1 (0.37) | KDM4ECYP4F2CYP4A11TSHRCA12 | |
| SCHEMBL21177461 | 0.79 | CYP4F2 (0.47) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL21179420 | 0.77 | HDAC3 (0.41) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL22918400 | 0.76 | HDAC4 (0.47) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL21596124 | 0.75 | HDAC4 (0.46) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL21177402 | 0.74 | KDM4E (0.46) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL21596132 | 0.72 | HDAC4 (0.39) | KDM4EHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL22918402 | 0.72 | HDAC3 (0.43) | KDM4EHDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615508-B | Amidine-substituted benzoyl derivatives useful as herbicides | 先正达参股股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-15 | — | — | US | disclosed |
| EP-3740470-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-11-05 | — | — | US | disclosed |
| WO-2019141740-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | GLRX3, DDT, BROX | KDM4E 548/4885HDAC3 222/4885HDAC4 633/4885 |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | GLRX3, DDT, BROX | KDM4E 548/4885HDAC3 222/4885HDAC4 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.