SCHEMBL2117768

SCHEMBL2117768

C=C(C)C(=O)OCCCCOCCOCC

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.79
TSHR P16473 5/20 0.65
ALDH1A1 P00352 4/20 0.48
HTT P42858 2/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
EPHX2 P34913 4/20 0.37
CES2 O00748 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20312879 0.98 THRB (0.76) THRBTSHRALDH1A1HTTPOLB
SCHEMBL8850646 0.98 THRB (0.75) THRBTSHRALDH1A1HTTPOLB
SCHEMBL8850634 0.98 THRB (0.75) THRBTSHRALDH1A1HTTPOLB
SCHEMBL8850956 0.98 THRB (0.75) THRBTSHRALDH1A1HTTPOLB
SCHEMBL2118746 0.96 THRB (0.79) THRBTSHRALDH1A1HTTPOLB
SCHEMBL15385988 0.96 THRB (0.85) THRBTSHRALDH1A1HTTPOLB
SCHEMBL1170964 0.96 THRB (0.78) THRBTSHRALDH1A1HTTPOLB
SCHEMBL29626882 0.95 THRB (0.82) THRBTSHRALDH1A1HTTPOLB
SCHEMBL3794443 0.94 THRB (0.75) THRBTSHRALDH1A1HTTPOLB
SCHEMBL3788969 0.94 THRB (0.75) THRBTSHRALDH1A1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
US-10899862-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-26 US disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
EP-3458118-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2019-03-27 EP disclosed
US-10196470-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2019-02-05 US disclosed
US-20180334520-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 US disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed
US-8318824-B2 Hydrophilic polyolefin sintered body ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-11-27 US disclosed
US-20120095121-A1 HYDROPHILIC POLYOLEFIN SINTERED BODY ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-04-19 US disclosed
EP-2174975-A1 HYDROPHILIC POLYOLEFIN SINTERED BODY Asahi Kasei Chemicals Corporation (JP) 2010-04-14 EP disclosed