Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20906057 | 0.88 | KDM4E (0.38) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3878733 | 0.82 | S1PR4 (0.33) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8168620 | 0.81 | KMT2A (0.44) | KMT2AMEN1KDM4ESMN1; SMN2POLB | |
| SCHEMBL2534992 | 0.79 | KMT2A (0.42) | KMT2AMEN1KDM4ESMN1; SMN2POLB | |
| SCHEMBL18614528 | 0.76 | HTT (0.41) | KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4595504 | 0.74 | SMN1; SMN2 (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17581161 | 0.74 | MAPT (0.38) | KMT2AMEN1KDM4ESMN1; SMN2POLB | |
| SCHEMBL13501522 | 0.74 | HCAR2 (0.33) | KMT2AMEN1 | |
| SCHEMBL4596233 | 0.73 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL10995423 | 0.72 | KMT2A (0.37) | KMT2AMEN1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |