SCHEMBL21177754

SCHEMBL21177754

CO[Si](C)(C)C(C)C(=O)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22614810 0.82 TSHR (0.39) TSHRTDP1L3MBTL1HCAR2NPSR1
SCHEMBL21180340 0.81 SMN1; SMN2 (0.44) TSHRSMN1; SMN2
SCHEMBL27891671 0.79 TSHR (0.40) TSHRTDP1L3MBTL1HCAR2SMN1; SMN2
SCHEMBL21182296 0.78 TSHR (0.43) TSHRTDP1L3MBTL1HCAR2
SCHEMBL28897933 0.77 TSHR (0.34) TSHR
SCHEMBL21177502 0.76 ALDH1A1 (0.39) TSHRTDP1SMN1; SMN2NPSR1
SCHEMBL28447355 0.73 TP53 (0.36)
SCHEMBL28448900 0.72 HCAR2 (0.34) TSHRTDP1HCAR2NPSR1
SCHEMBL21179456 0.70 ALDH1A1 (0.45) TSHRTDP1L3MBTL1HCAR2SMN1; SMN2
SCHEMBL21179474 0.68 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
CN-111601866-B Silicone adhesive composition, cured product, adhesive film, and adhesive tape 信越化学工业株式会社 2022-09-06 CN disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
CN-111601866-A Silicone adhesive composition, adhesive film, and adhesive tape 信越化学工业株式会社 2020-08-28 CN disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed