SCHEMBL21177765

SCHEMBL21177765

[NaH].[c]1scc2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28130734 0.95 CYP2A6 (0.33) CYP2A6ALOX12
SCHEMBL28219489 0.78
SCHEMBL4477160 0.67 CYP2A6 (0.39) CYP2A6
SCHEMBL700107 0.65 CYP2A6 (0.44) CYP2A6ALOX12
SCHEMBL2516748 0.65 ALDH1A1 (0.46) CYP2A6
SCHEMBL1976862 0.60
Naphthalene SCHEMBL2696286 0.60 CYP2A6 (0.89) CYP2A6ALOX12
Naphthalene SCHEMBL2696131 0.60 CYP2A6 (0.89) CYP2A6ALOX12
Naphthalene SCHEMBL51882 0.60 CYP2A6 (0.89) CYP2A6ALOX12
Naphthalene SCHEMBL5950127 0.60 CYP2A6 (0.89) CYP2A6ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3741764-A1 SYNTHESIS METHOD FOR BORONIC ACID ESTER COMPOUND, AND SODIUM SALT OF BORONIC ACID ESTER COMPOUND AND SYNTHESIS METHOD THEREFOR Kobelco Eco-Solutions Co., Ltd (JP) 2020-11-25 EP disclosed
CN-111801335-A Synthesis method of boronic acid ester compound, sodium salt of boronic acid ester compound and synthesis method thereof 株式会社神钢环境舒立净 2020-10-20 CN disclosed
WO-2019142854-A1 SYNTHESIS METHOD FOR BORONIC ACID ESTER COMPOUND, AND SODIUM SALT OF BORONIC ACID ESTER COMPOUND AND SYNTHESIS METHOD THEREFOR 株式会社神鋼環境ソリューション 2019-07-25 WO disclosed