Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12086987 | 0.86 | TDP1 (0.62) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL3824611 | 0.84 | TDP1 (0.64) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL2257980 | 0.84 | TDP1 (0.64) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL21629143 | 0.83 | CES2 (0.54) | TDP1L3MBTL1TSHRMEN1NPC1 | |
| SCHEMBL30527914 | 0.82 | TDP1 (0.62) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL395027 | 0.82 | TDP1 (0.62) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL30356232 | 0.81 | TDP1 (0.53) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL20298737 | 0.81 | TDP1 (0.60) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL1800860 | 0.81 | TDP1 (0.60) | TDP1L3MBTL1TSHRCA1CA2 | |
| SCHEMBL11151271 | 0.81 | TDP1 (0.60) | TDP1L3MBTL1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143273-A1 | NOVEL AMIDINE INHIBITORS OF FACTOR XA | ООО "ФармаДиол" | 2019-07-25 | — | — | WO | disclosed |