Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.42 |
| ▸ | CDK7 | P50613 | 4/20 | 0.42 |
| ▸ | CDK9 | P50750 | 4/20 | 0.42 |
| ▸ | CCNH | P51946 | 4/20 | 0.42 |
| ▸ | CCNK | O75909 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176607 | 0.90 | CCNK (0.44) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21184312 | 0.85 | CCNK (0.47) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL30853845 | 0.85 | CCNK (0.47) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21188370 | 0.84 | CCNK (0.52) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL29509375 | 0.84 | CDK7 (0.45) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21184427 | 0.84 | CCNK (0.47) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21178909 | 0.84 | CDK7 (0.44) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21184297 | 0.84 | CDK7 (0.44) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21184423 | 0.84 | CCNK (0.54) | CCNT1CDK7CDK9CCNHCCNK | |
| SCHEMBL21184315 | 0.82 | CDK7 (0.45) | CCNT1CDK7CDK9CCNHCCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740206-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-3740206-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019143730-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |