Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 11/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 11/20 | 0.47 |
| ▸ | CDK7 | P50613 | 10/20 | 0.47 |
| ▸ | CCNH | P51946 | 10/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.47 |
| ▸ | CDK9 | P50750 | 9/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.47 |
| ▸ | CDK2 | P24941 | 8/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184312 | 1.00 | CCNK (0.47) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184427 | 0.91 | CCNK (0.47) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184297 | 0.89 | CDK7 (0.44) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21178909 | 0.89 | CDK7 (0.44) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184423 | 0.89 | CCNK (0.54) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184315 | 0.89 | CDK7 (0.45) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184310 | 0.87 | CDK7 (0.43) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL24176607 | 0.86 | CCNK (0.44) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184416 | 0.85 | CDK7 (0.49) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21178882 | 0.85 | CCNT1 (0.42) | CCNKCDK12CDK7CCNHCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918592-B2 | Inhibitors of cyclin dependent kinase 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2024-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11918592-B2 | Inhibitors of cyclin dependent kinase 7 (CDK7) | CDK7, CDK3, CCNK | CCNK 3/4885CDK12 27/4885CDK7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.