Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144406 | 0.83 | SLC6A4 (0.35) | SLC6A4SLC6A3MAPT | |
| SCHEMBL25973804 | 0.72 | ALDH1A1 (0.34) | SLC6A4SLC6A3MAPT | |
| SCHEMBL956270 | 0.68 | SLC6A4 (0.33) | SLC6A4SLC6A3MAPT | |
| SCHEMBL13799456 | 0.67 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL21179109 | 0.67 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL5497280 | 0.67 | SLC6A4 (0.32) | SLC6A4SLC6A3 | |
| SCHEMBL3246813 | 0.66 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL8343403 | 0.66 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL17971808 | 0.66 | — | — | |
| SCHEMBL14981578 | 0.66 | SLC6A4 (0.33) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740483-A1 | QUINOXALINONE COMPOUNDS, COMPOSITIONS, METHODS, AND KITS FOR INCREASING GENOME EDITING EFFICIENCY | Vertex Pharmaceuticals Incorporated (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019143677-A1 | QUINOXALINONE COMPOUNDS, COMPOSITIONS, METHODS, AND KITS FOR INCREASING GENOME EDITING EFFICIENCY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-07-25 | — | — | WO | disclosed |