Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179334 | 1.00 | GPR6 (0.41) | GPR6IKBKBCHUKPIK3CDPIK3CA | |
| SCHEMBL21191755 | 0.85 | GPR119 (0.55) | PIK3CDPIK3CAGPR119PIK3CBPIK3CG | |
| Fumaric Acid SCHEMBL10370924 | 0.82 | HRH1 (0.44) | GPR6HCRTR1HCRTR2 | |
| Fumaric Acid SCHEMBL10372505 | 0.82 | HRH1 (0.44) | GPR6HCRTR1HCRTR2 | |
| SCHEMBL26601574 | 0.81 | GPR119 (0.43) | GPR119ELANE | |
| SCHEMBL10369852 | 0.81 | HRH3 (0.43) | GPR6TBK1 | |
| SCHEMBL15691866 | 0.79 | GPR119 (0.43) | GPR6IKBKBCHUKGPR119ELANE | |
| SCHEMBL25246190 | 0.79 | IKBKB (0.43) | IKBKBCHUKNAMPT | |
| SCHEMBL31302342 | 0.79 | IKBKB (0.43) | IKBKBCHUKNAMPT | |
| SCHEMBL25292960 | 0.75 | IKBKB (0.40) | IKBKBCHUKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |