Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177157 | 0.86 | CYP4F2 (0.47) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL31121872 | 0.86 | CYP4F2 (0.47) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL21596127 | 0.85 | TSHR (0.44) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL7949545 | 0.85 | TSHR (0.44) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL4268094 | 0.84 | KDM4E (0.44) | TSHRCA1CA2CA9HSD17B10 | |
| SCHEMBL22918491 | 0.84 | SMN1; SMN2 (0.43) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL21177214 | 0.84 | TSHR (0.40) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL21596128 | 0.81 | CA1 (0.40) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL28709360 | 0.81 | CA12 (0.42) | CA1CA2CA12CA9CA7 | |
| SCHEMBL21596130 | 0.80 | TSHR (0.39) | TSHRCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409616-B | Preparation method of 3-bromomethyl-2-halo-4-alkylsulfonylbenzoate | 北京颖泰嘉和生物科技股份有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-111615508-B | Amidine-substituted benzoyl derivatives useful as herbicides | 先正达参股股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-117822000-A | Cyclosultone intermediate and electrooxidation preparation method thereof | 厦门杰青连续流科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-3740470-B1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-15 | — | — | US | disclosed |
| CN-108409616-B | Preparation method of 3-bromomethyl-2-halo-4-alkylsulfonylbenzoate | 北京颖泰嘉和生物科技股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-3740470-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-11-05 | — | — | US | disclosed |
| CN-111615508-A | Amidine substituted benzoyl derivatives useful as herbicides | 先正达参股股份有限公司 | 2020-09-01 | — | — | CN | disclosed |
| WO-2019141740-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | GLRX3, DDT, BROX | TSHR 1441/4885CA1 691/4885CA2 167/4885 |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | GLRX3, DDT, BROX | TSHR 1441/4885CA1 691/4885CA2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.