Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2122433 | 0.98 | TSHR (0.48) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL28883851 | 0.88 | TSHR (0.54) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL27859984 | 0.83 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL27859986 | 0.83 | TSHR (0.40) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL10496026 | 0.79 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL10983427 | 0.79 | TSHR (0.46) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL9666722 | 0.78 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL16209873 | 0.77 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL28256465 | 0.77 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL11140368 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003246-B | Synthesis method of alpha-ketoglutaric acid | 邯郸市瑞田农药有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-118146083-A | Preparation method of alpha-ketoglutaric acid and derivatives thereof | 中国农业科学院饲料研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-116003246-A | Synthesis method of alpha-ketoglutaric acid | 邯郸市瑞田农药有限公司 | 2023-04-25 | — | — | CN | claimed |
| US-20140187815-A1 | Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1 | ZHANG GUOJI (CN) | 2014-07-03 | — | — | US | claimed |
| US-8754256-B2 | Process for preparation of L-Arginine α-ketoglutarate 1:1 and 2:1 | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD. (CHINA) (CN) | 2014-06-17 | — | — | US | claimed |
| US-8680329-B2 | Process for preparation of α-ketoglutaric acid | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD. (CHINA) (CN) | 2014-03-25 | — | — | US | claimed |
| US-20120095261-A1 | Process for preparation of alpha-ketoglutaric acid | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | claimed |
| US-20120095260-A1 | Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1 | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | claimed |
| CN-116003246-B | Synthesis method of alpha-ketoglutaric acid | 邯郸市瑞田农药有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118146083-A | Preparation method of alpha-ketoglutaric acid and derivatives thereof | 中国农业科学院饲料研究所 | 2024-06-07 | — | — | CN | disclosed |
| CN-118146083-A | Preparation method of alpha-ketoglutaric acid and derivatives thereof | 中国农业科学院饲料研究所 | 2024-06-07 | — | — | CN | disclosed |
| CN-116003246-A | Synthesis method of alpha-ketoglutaric acid | 邯郸市瑞田农药有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-108486173-B | Preparation method of alpha-ketoglutaric acid | 河南巨龙生物工程股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-109295023-B | Glutamate oxidase mutant, nucleic acid molecule, application and method for preparing ketoglutaric acid | 南京红杉生物科技有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-102584568-A | Process for preparation of alpha-ketoglutaric acid | GUOJI ZHANG | 2012-07-18 | — | — | CN | disclosed |
| US-20120095260-A1 | Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1 | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | disclosed |
| US-20120095261-A1 | Process for preparation of alpha-ketoglutaric acid | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | disclosed |
| US-20120095260-A1 | Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1 | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | disclosed |
| US-20120095261-A1 | Process for preparation of alpha-ketoglutaric acid | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | disclosed |
| US-20120095261-A1 | Process for preparation of alpha-ketoglutaric acid | TIANJIN TIANCHENG PHARMACEUTICAL CO., LTD.(CHINA) | 2012-04-19 | — | — | US | disclosed |