Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118005 | 0.83 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8625732 | 0.82 | LMNA (0.36) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| Water SCHEMBL2122433 | 0.81 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10978109 | 0.79 | TSHR (0.38) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL161711 | 0.76 | NAALAD2 (0.45) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL28883851 | 0.75 | TSHR (0.54) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11056460 | 0.74 | TSHR (0.40) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL7964223 | 0.74 | NAALAD2 (0.44) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9429165 | 0.74 | NAALAD2 (0.44) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL2119588 | 0.74 | ALDH1A1 (0.43) | TSHRNAALAD2ALDH1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102976927-A | Preparation method of calcium alpha-ketoglutarate | TIANJIN TIANCHENG PHARMACEUTICAL CO LTD | 2013-03-20 | — | — | CN | claimed |
| CN-102584568-A | Process for preparation of alpha-ketoglutaric acid | GUOJI ZHANG | 2012-07-18 | — | — | CN | claimed |
| CN-102531968-A | Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1 | GUOJI ZHANG | 2012-07-04 | — | — | CN | claimed |
| CN-104109698-A | Enzymic method for producing [alpha]-ketoglutaric acid | SHANGHAI RES AND DEV CT OF IND BIOTECHNOLOGY | 2014-10-22 | — | — | CN | disclosed |
| CN-102976927-A | Preparation method of calcium alpha-ketoglutarate | TIANJIN TIANCHENG PHARMACEUTICAL CO LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-102584568-A | Process for preparation of alpha-ketoglutaric acid | GUOJI ZHANG | 2012-07-18 | — | — | CN | disclosed |
| CN-102531968-A | Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1 | GUOJI ZHANG | 2012-07-04 | — | — | CN | disclosed |