Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177539 | 0.87 | KLKB1 (0.40) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL21177639 | 0.83 | KLKB1 (0.45) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL19779895 | 0.80 | KLKB1 (0.57) | KLKB1MAP4K1MAPT | |
| SCHEMBL21177161 | 0.77 | KLKB1 (0.42) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL19780120 | 0.73 | KLKB1 (0.40) | KLKB1MAP4K1 | |
| SCHEMBL21177567 | 0.72 | KLKB1 (0.35) | KLKB1MAP4K1 | |
| SCHEMBL21177362 | 0.71 | KLKB1 (0.38) | KLKB1MAP4K1ALDH1A1TSHRLMNA | |
| SCHEMBL20531521 | 0.71 | KLKB1 (0.43) | KLKB1ALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL21177310 | 0.71 | KLKB1 (0.32) | KLKB1MAP4K1 | |
| SCHEMBL29302757 | 0.71 | KLKB1 (0.34) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |