Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177639 | 0.85 | KLKB1 (0.45) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL21177781 | 0.81 | KLKB1 (0.36) | KLKB1MAP4K1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL21177327 | 0.78 | S1PR1 (0.37) | KLKB1ALDH1A1 | |
| SCHEMBL21180345 | 0.77 | KLKB1 (0.40) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL21177539 | 0.77 | KLKB1 (0.40) | KLKB1MAP4K1ALDH1A1TSHRMAPK1 | |
| SCHEMBL19779896 | 0.76 | KLKB1 (0.62) | KLKB1MAP4K1ALDH1A1 | |
| SCHEMBL21177362 | 0.75 | KLKB1 (0.38) | KLKB1MAP4K1ALDH1A1TSHR | |
| SCHEMBL21177142 | 0.73 | KLKB1 (0.36) | KLKB1MAP4K1ALDH1A1 | |
| SCHEMBL19780407 | 0.73 | KLKB1 (0.42) | KLKB1MAPK1NPSR1 | |
| SCHEMBL21177545 | 0.71 | KLKB1 (0.34) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |