Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16648170 | 0.92 | ATM (0.85) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL28420107 | 0.90 | ATM (0.81) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL24492853 | 0.88 | ATM (0.77) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL24493202 | 0.88 | ATM (0.77) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL9975007 | 0.86 | ATM (0.74) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| Alcohol SCHEMBL28257176 | 0.86 | ATM (0.74) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL9974964 | 0.86 | ATM (0.74) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| Biphenyl SCHEMBL28814351 | 0.84 | ATM (0.72) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| Biphenyl SCHEMBL25263755 | 0.84 | ATM (0.72) | ATMCYP2A6ALDH1A1NOTUMNPC1 | |
| SCHEMBL6682176 | 0.84 | ATM (0.72) | ATMCYP2A6ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100488952-C | 5-phenyl pyridine, its preparation method and intermediate product and uses in controlling harmful fungus | BASF AG (DE) | 2009-05-20 | — | — | CN | claimed |
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | claimed |
| US-7465735-B2 | crop protection agents for controlling harmful fungi; improved activity; 6-chloro-2-(N'-isopropylidene-hydrazino)-5-(2,4,6-trifluorophenyl)pyrimidine-4-yl]-((S)-1-trifluoromethylethyl)amine; against Septoria Leaf Blotch of Wheat, Net Blotch of Barley and Mildew of Cucumber | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-16 | — | — | US | claimed |
| US-7449471-B2 | 5-phenylpyrimidines, their preparation, compositions comprising them and their use | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-11 | — | — | US | claimed |
| JP-2008528535-A | — | — | 2008-07-31 | — | — | JP | claimed |
| US-20080146593-A1 | Substituted 5-Phenyl Pyrimidines I In Therapy | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | US | claimed |
| CN-101111250-A | Substituted 5-phenylpyrimidines I for therapy | BASF AG (DE) | 2008-01-23 | — | — | CN | claimed |
| EP-1845991-A2 | SUBSTITUTED 5-PHENYL PYRIMIDINES I IN THERAPY | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-24 | — | — | EP | claimed |
| EP-1565436-A4 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2007-07-18 | — | — | EP | claimed |
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | GYPSER ANDREAS | 2007-06-28 | — | — | US | claimed |
| US-5753139-A | High contrast distorted helix effect electro-optic devices and tight ferroelectric pitch ferroelectric pitch ferroelectric liquid crystal compositions useful therein | DISPLAYTECH, INC. (US) | 1998-05-19 | — | — | US | claimed |
| US-5662828-A | Compound having unsaturated side chain, process for preparing the same, liquid crystalline polymer prepared from the same, liquid crystal mixture and display element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-09-02 | — | — | US | claimed |
| US-5554317-A | POLYSILOXANE LIQUID CRYSTALLINE POLYMERS FORMED BY GRAFT POLYMERIZING AT LEAST ONE UNSATURATED COMPOUND WITH ONE OR MORE AROMATIC OR HETEROAROMATIC RINGS, OPTIONAL ETHER GROUP AND OPTIONAL ASYMMETRIC C ON POLYALKYLHYDROSILOXANE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-09-10 | — | — | US | claimed |
| US-5539555-A | High contrast distorted helex effect electro-optic devices and tight ferroelectric pitch ferroelectric liquid crystal compositions useful therein | DISPLAYTECH, INC. (US) | 1996-07-23 | — | — | US | claimed |
| EP-0634469-A1 | Compound having unsaturated side-chain, process for preparing the same, liquid crystalline polymer prepared from the same, liquid crystal mixture and display element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | claimed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | claimed |
| EP-0295370-B1 | LIQUID-CRYSTALLINE 5-PHENYL PYRIMIDINE DERIVATIVES WITH AN SC OR SC (ASTERISK) PHASE, AND METHOD FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | claimed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | claimed |
| WO-1992001766-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS | DISPLAYTECH, INC. (US) | 1992-02-06 | — | — | WO | claimed |
| US-4906752-A | Liquid-crystal 5-phenylpyrimidine derivatives having sc or sc* phases and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149551-A1 | 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE | CBR1, CBR3, NTPCR | ATM 3647/4885CYP2A6 383/4885ALDH1A1 356/4885 |
| US-20080146593-A1 | Substituted 5-Phenyl Pyrimidines I In Therapy | NR1H2, NR1H3, NR1I2 | ATM 3160/4885CYP2A6 94/4885ALDH1A1 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.