SCHEMBL28420107

SCHEMBL28420107

OBO.c1ccc(-c2cncnc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.81
CYP2A6 P11509 2/20 0.54
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NOTUM Q6P988 1/20 0.44
HDAC4 P56524 1/20 0.44
ALDH1A1 P00352 2/20 0.43
EPHB4 P54760 1/20 0.42
TEK Q02763 1/20 0.42
GRM5 P41594 1/20 0.41
MKNK1 Q9BUB5 2/20 0.40
MKNK2 Q9HBH9 2/20 0.40
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
CYP19A1 P11511 1/20 0.39
CYP11B1 P15538 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2118053 0.90 ATM (1.00) ATMCYP2A6NPC1NFKB1RAB9A
SCHEMBL16648170 0.83 ATM (0.85) ATMCYP2A6NPC1NFKB1RAB9A
Alcohol SCHEMBL28257176 0.82 ATM (0.74) ATMCYP2A6NPC1NFKB1RAB9A
SCHEMBL24492853 0.79 ATM (0.77) ATMCYP2A6NPC1NFKB1RAB9A
SCHEMBL5954583 0.79 CYP2A6 (0.68) ATMCYP2A6NPC1RAB9ASMN1; SMN2
SCHEMBL24493202 0.79 ATM (0.77) ATMCYP2A6NPC1NFKB1RAB9A
Biphenyl SCHEMBL522299 0.79 ALDH1A1 (0.69) ATMNPC1RAB9ASMN1; SMN2NOTUM
Biphenyl SCHEMBL4442099 0.79 ALDH1A1 (0.69) ATMNPC1RAB9ASMN1; SMN2NOTUM
SCHEMBL9974964 0.77 ATM (0.74) ATMCYP2A6NPC1NFKB1RAB9A
SCHEMBL9975007 0.77 ATM (0.74) ATMCYP2A6NPC1NFKB1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187201-A Compound and organic electroluminescent device 清华大学 2020-05-22 CN disclosed