Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946243 | 0.89 | KDM4E (0.39) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL15946239 | 0.89 | KDM4E (0.39) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL21180700 | 0.82 | KDM4E (0.40) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL21180582 | 0.82 | KDM4E (0.40) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL21180545 | 0.82 | KDM4E (0.40) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL21180578 | 0.82 | KDM4E (0.40) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL20706786 | 0.82 | KDM4E (0.44) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL20706805 | 0.80 | KDM4E (0.50) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL14725731 | 0.80 | KDM4E (0.37) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL23046453 | 0.80 | KDM4E (0.44) | SIRT2SIRT1KDM4EL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |