Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071701 | 0.86 | NOTUM (0.83) | NOTUMCYP2C9CYP2C19DEGS1CA12 | |
| SCHEMBL5790870 | 0.84 | NOTUM (0.67) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL21180885 | 0.84 | NOTUM (0.58) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL12508733 | 0.83 | NOTUM (0.69) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL31381163 | 0.82 | NOTUM (0.70) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL25435393 | 0.82 | NOTUM (0.64) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL18395507 | 0.82 | NOTUM (0.64) | NOTUMTDP1KDM4ELMNAMAPT | |
| Hydrochloric Acid SCHEMBL34469418 | 0.81 | NOTUM (0.68) | NOTUMGAATDP1KDM4EABL1 | |
| SCHEMBL21542280 | 0.81 | NOTUM (0.62) | NOTUMTDP1KDM4ELMNAMAPT | |
| SCHEMBL23582498 | 0.81 | NOTUM (0.48) | NOTUMGAATDP1KDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497709-A | Pyrimidine derivatives | ASKA 制药株式会社 | 2025-02-21 | — | — | CN | disclosed |
| EP-3221304-B1 | NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | LILLY CO ELI (US) | 2019-07-24 | — | — | EP | disclosed |