Trifluoromethanesulfonamide

Trifluoromethanesulfonamide

SCHEMBL2118135

CCCCCC[n+]1ccccc1.NS(=O)(=O)C(F)(F)F.NS(=O)(=O)C(F)(F)F

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.65
CHRM2 P08172 2/20 0.65
ADRA2A P08913 2/20 0.65
ADORA3 P0DMS8 2/20 0.65
CHRM1 P11229 2/20 0.65
SLC6A2 P23975 2/20 0.65
SLC6A4 P31645 2/20 0.65
SLC6A3 Q01959 2/20 0.65
ABCB11 O95342 1/20 0.65
ESR1 P03372 1/20 0.65
PGR P06401 1/20 0.65
HTR1A P08908 1/20 0.65
DRD1 P21728 1/20 0.65
TBXA2R P21731 1/20 0.65
PTGS1 P23219 1/20 0.65
PDE4A P27815 1/20 0.65
ADRA1A P35348 1/20 0.65
OPRM1 P35372 1/20 0.65
DRD3 P35462 1/20 0.65
KCNH2 Q12809 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonamide SCHEMBL2295366 0.93 ACHE (0.53) ACHECHRM2ADRA2AADORA3CHRM1
Cetylpyridinium SCHEMBL28390298 0.87 KCNH2 (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoromethanesulfonic Acid SCHEMBL28372122 0.87 KCNH2 (0.65) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL2829737 0.87 ACHE (0.65) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL2834622 0.87 ACHE (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoromethanesulfonic Acid SCHEMBL29252066 0.87 KCNH2 (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoromethanesulfonic Acid SCHEMBL712183 0.87 KCNH2 (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoromethanesulfonic Acid SCHEMBL29252544 0.87 KCNH2 (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoromethanesulfonic Acid SCHEMBL16699863 0.85 KCNH2 (0.61) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL3610312 0.84 ACHE (0.61) ACHECHRM2ADRA2AADORA3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281930-B1 ODOUR SAMPLE DIEHL DEFENCE GMBH & CO KG (DE) 2020-09-30 EP claimed
EP-2583096-B1 METHOD FOR DETECTING PEROXIDE EXPLOSIVES UNIV BONN RHEINISCHE FRIEDRICH WILHELMS (DE) 2019-04-10 EP claimed
US-8603270-B2 Odor samples of peroxidic explosives RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN (DE) 2013-12-10 US claimed
US-20120090744-A1 ODOR SAMPLES OF PEROXIDIC EXPLOSIVES Diehl Bgt. Defence GmbH & Co., KG (DE) 2012-04-19 US claimed
US-8603270-B2 Odor samples of peroxidic explosives RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN (DE) 2013-12-10 US disclosed
US-20120090744-A1 ODOR SAMPLES OF PEROXIDIC EXPLOSIVES Diehl Bgt. Defence GmbH & Co., KG (DE) 2012-04-19 US disclosed