SCHEMBL21183186

SCHEMBL21183186

Cc1ccc(C(=O)c2ccccc2-c2ccc(C)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.62
ALDH1A1 P00352 4/20 0.54
LMNA P02545 3/20 0.54
TDP1 Q9NUW8 2/20 0.53
MAPT P10636 4/20 0.50
NPSR1 Q6W5P4 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CDC25B P30305 1/20 0.50
ATM Q13315 1/20 0.50
KDM4E B2RXH2 1/20 0.50
USP2 O75604 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HPGD P15428 1/20 0.50
MAPK13 O15264 1/20 0.49
MAPK12 P53778 1/20 0.49
MAPK11 Q15759 1/20 0.49
MAPK14 Q16539 1/20 0.49
RAB9A P51151 1/20 0.49
CYP2C9 P11712 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843143 1.00 AKR1C3 (0.62) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL28116437 0.95 AKR1C3 (0.66) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL5693606 0.95 AKR1C3 (0.61) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL23758169 0.92 SLC6A4 (0.56) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL15660913 0.92 SLC6A4 (0.56) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL30448294 0.91 AKR1C3 (0.67) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL16882044 0.90 KMT2A (0.48) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL29066920 0.86 ALDH1A1 (0.67) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL29367957 0.86 AKR1C3 (0.51) AKR1C3ALDH1A1LMNATDP1MAPT
SCHEMBL27415726 0.86 AKR1C3 (0.51) AKR1C3ALDH1A1LMNATDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514139-A1 FLUORINE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME LG Chem, Ltd. (KR) 2019-07-24 EP disclosed