Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.68 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | GRB2 | P62993 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | TPH1 | P17752 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258519 | 1.00 | PTPN1 (0.68) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2867832 | 1.00 | PTPN1 (0.68) | PTPN1SLC7A5PTGS1ALPIPKM | |
| Hydrochloric Acid SCHEMBL2309162 | 0.98 | PTPN1 (0.67) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL17658724 | 0.89 | PTPN1 (0.54) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL14945062 | 0.88 | PTPN1 (0.74) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL4946473 | 0.87 | PTPN1 (0.52) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL4946470 | 0.87 | PTPN1 (0.52) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL16080173 | 0.84 | ACACB (0.50) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2058886 | 0.84 | ACACB (0.53) | PTPN1ITGB3ITGA2BACACBPTGS2 | |
| SCHEMBL2311151 | 0.84 | ACACB (0.50) | PTPN1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024316-A | 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof | 南开大学 | 2023-11-10 | — | — | CN | claimed |
| US-20180355025-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS INC. | 2018-12-13 | — | — | US | claimed |
| EP-2722051-A1 | Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus | Seattle Genetics, Inc. (US) | 2014-04-23 | — | — | EP | claimed |
| US-20090018086-A1 | Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus | SEATTLE GENETICS, INC. (US) | 2009-01-15 | — | — | US | claimed |
| EP-1922345-A2 | PROCESS FOR THE PREPARATION OF COPOLYMER-1 | Chan, Wai Hong (US) | 2008-05-21 | — | — | EP | claimed |
| EP-1917020-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | Seattle Genetics, Inc. (US) | 2008-05-07 | — | — | EP | claimed |
| US-20070141663-A1 | Process for the preparation of copolymer-1 | DING JINGUO | 2007-06-21 | — | — | US | claimed |
| WO-2007022193-A2 | PROCESS FOR THE PREPARATION OF COPOLYMER-1 | CHAN WAI HONG (US) | 2007-02-22 | — | — | WO | claimed |
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| EP-0370454-B1 | Renin-inhibiting amino diol derivatives | HOECHST AG (DE) | 1994-04-20 | — | — | EP | claimed |
| EP-0373497-A2 | Dipeptide derivatives with an enzyme-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | claimed |
| EP-0372537-A2 | Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | claimed |
| EP-0370383-A2 | Renin-inhibiting dipeptides, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0370382-A2 | Urea dipeptide derivatives with a renin-inhibiting activity, process to produce them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0370454-A2 | Renin-inhibiting amino diol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0329013-A2 | Renin-inhibiting amino acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | claimed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | claimed |
| EP-0310015-A2 | Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | claimed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180355025-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | PTPN1 4207/4885SLC7A5 50/4885PTGS1 4600/4885 |
| US-20090018086-A1 | Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus | MMAB, DNPEP, MARCKS | PTPN1 4124/4885SLC7A5 39/4885PTGS1 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.