Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311154 | 1.00 | ACACB (0.50) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| SCHEMBL3729750 | 1.00 | ACACB (0.50) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| SCHEMBL16080173 | 1.00 | ACACB (0.50) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| Hydrochloric Acid SCHEMBL7325406 | 0.98 | ACACB (0.49) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| Hydrochloric Acid SCHEMBL29398263 | 0.98 | ACACB (0.49) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| Hydrochloric Acid SCHEMBL3745279 | 0.98 | ACACB (0.49) | ACACBPTPN1SLC7A5LTA4HABCB1 | |
| SCHEMBL21029441 | 0.90 | PTPN1 (0.53) | ACACBPTPN1SLC7A5LTA4HPPARA | |
| SCHEMBL16355895 | 0.90 | PTPN1 (0.47) | ACACBPTPN1SLC7A5LTA4HITGB3 | |
| SCHEMBL4370256 | 0.90 | PTPN1 (0.53) | ACACBPTPN1SLC7A5LTA4HPPARA | |
| SCHEMBL22170839 | 0.89 | ACACB (0.46) | ACACBPTPN1SLC7A5LTA4HABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448545-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | Chemi SPA (IT) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401540-A | Manufacturing process for the production of linaclotide | 凯米股份公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023110781-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2023-06-22 | — | — | WO | disclosed |
| EP-4194464-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | Chemi SPA (IT) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023075435-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | 주식회사 베르티스 | 2023-05-04 | — | — | WO | disclosed |
| US-20230133465-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS | ALZHEON, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | NANJING NUOYUAN MEDICAL DEVICES CO., LTD (CN) | 2022-08-25 | — | — | US | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11053192-B2 | Compositions and methods for treating and preventing neurodegenerative disorders | ALZHEON, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2004030635-A2 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | TARGEGEN, INC. (US) | 2004-04-15 | — | — | WO | disclosed |
| US-20040038993-A1 | Pyrazolo[1,5a]pyrimidine compounds as antiviral agents | NEOGENESIS PHARMACEUTICALS, INC. | 2004-02-26 | — | — | US | disclosed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |
| EP-0594588-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | Pfizer Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| EP-0358398-B1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991013054-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1991-09-05 | — | — | WO | disclosed |
| EP-0358398-A1 | Cycloalkyl-substituted glutaramide antihypertensive agents | Pfizer Limited (GB) | 1990-03-14 | — | — | EP | disclosed |
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133465-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS | PSEN2, CLN6, PSEN1 | ACACB 201/4885PTPN1 4390/4885SLC7A5 4232/4885 |
| US-11053192-B2 | Compositions and methods for treating and preventing neurodegenerative disorders | PSEN2, CLN6, PSEN1 | ACACB 201/4885PTPN1 4390/4885SLC7A5 4232/4885 |
| US-20040038993-A1 | Pyrazolo[1,5a]pyrimidine compounds as antiviral agents | RNGTT, PNP, ZC3HAV1 | ACACB 842/4885PTPN1 1496/4885SLC7A5 3750/4885 |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | FOLR1, FOLR2, DHFR | ACACB 4826/4885PTPN1 4335/4885SLC7A5 50/4885 |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | WEE1, NOTUM, WEE2 | ACACB 2758/4885PTPN1 2822/4885SLC7A5 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.