Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594028 | 0.81 | MEN1 (0.43) | MEN1KMT2ATMPRSS4USP30DPP4 | |
| SCHEMBL1344704 | 0.81 | KDM4E (0.43) | MEN1KMT2ATMPRSS4USP30DEGS1 | |
| SCHEMBL402112 | 0.79 | DPP4 (0.51) | MEN1KMT2ATMPRSS4USP30DPP4 | |
| SCHEMBL8989496 | 0.78 | TMPRSS4 (0.47) | MEN1KMT2ATMPRSS4USP30DEGS1 | |
| SCHEMBL13593262 | 0.77 | MEN1 (0.43) | MEN1KMT2ATMPRSS4USP30DPP4 | |
| SCHEMBL10164879 | 0.77 | MEN1 (0.43) | MEN1KMT2ATMPRSS4USP30DPP4 | |
| SCHEMBL24991566 | 0.76 | MEN1 (0.45) | MEN1KMT2ATMPRSS4USP30DEGS1 | |
| SCHEMBL479494 | 0.76 | KDM4E (0.46) | MEN1KMT2ATMPRSS4USP30DEGS1 | |
| SCHEMBL247841 | 0.76 | KDM4E (0.57) | MEN1KMT2ATMPRSS4USP30DEGS1 | |
| SCHEMBL30401857 | 0.76 | KDM4E (0.46) | MEN1KMT2ATMPRSS4USP30DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234237-A1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-12-12 | — | — | WO | disclosed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |