Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.59 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.59 |
| ▸ | CDK7 | P50613 | 15/20 | 0.59 |
| ▸ | CCNH | P51946 | 15/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.59 |
| ▸ | CDK2 | P24941 | 12/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.59 |
| ▸ | CDK9 | P50750 | 11/20 | 0.59 |
| ▸ | MNAT1 | P51948 | 11/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184304 | 0.88 | CCNK (0.73) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL21184408 | 0.81 | CCNK (0.61) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL21184589 | 0.76 | CCNK (0.64) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL21184348 | 0.76 | CCNK (0.85) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL30554768 | 0.76 | CCNK (0.44) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL21629046 | 0.76 | CCNK (0.44) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL29488127 | 0.76 | CLK1 (0.52) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL25602821 | 0.75 | CCNE1 (0.72) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL21179226 | 0.75 | CCNK (0.65) | CCNKCDK12CDK7CCNHCCNE1 | |
| SCHEMBL25329327 | 0.74 | CDK7 (0.89) | CCNKCDK12CDK7CCNHCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143730-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |