Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22813133 | 0.92 | FAAH (0.46) | FAAHCNR2CNR1POLBEPHX2 | |
| SCHEMBL10188498 | 0.81 | POLB (0.52) | CNR2CNR1POLBALDH1A1MEN1 | |
| SCHEMBL23748298 | 0.81 | POLB (0.47) | FAAHCNR2CNR1POLBALDH1A1 | |
| SCHEMBL10188493 | 0.80 | POLB (0.60) | POLBALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL23748245 | 0.79 | POLB (0.46) | FAAHCNR2CNR1POLBALDH1A1 | |
| SCHEMBL21185145 | 0.79 | POLB (0.50) | POLBEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL21259220 | 0.78 | POLB (0.62) | POLBALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL10188488 | 0.78 | POLB (0.64) | POLBALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL19588885 | 0.78 | POLB (0.58) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL24246647 | 0.76 | FAAH (0.50) | FAAHCNR2CNR1EPHX2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247993-B2 | Pyridone derivative, composition and use as antiviral drug thereof | JIANGXI CAISHI PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| WO-2019141179-A1 | PYRIDONE DERIVATIVE, COMPOSITION THEREOF AND APPLICATION THEREOF AS ANTI-INFLUENZA DRUG | 银杏树药业(苏州)有限公司 | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247993-B2 | Pyridone derivative, composition and use as antiviral drug thereof | PNP, POLB, POLA1 | FAAH 3464/4885CNR2 4358/4885CNR1 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.