Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GHSR | Q92847 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119088 | 0.88 | TRIM24 (0.60) | TRIM24ALDH1A1POLBCYP3A4SMN1; SMN2 | |
| SCHEMBL2120619 | 0.88 | TRIM24 (0.57) | TRIM24ALDH1A1POLBCYP3A4MAPT | |
| SCHEMBL2117223 | 0.85 | TRIM24 (0.55) | TRIM24ALDH1A1POLBCYP3A4MAPT | |
| SCHEMBL2120627 | 0.84 | TRIM24 (0.59) | TRIM24ALDH1A1POLBCYP3A4SMN1; SMN2 | |
| SCHEMBL2121409 | 0.82 | TRIM24 (0.55) | TRIM24ALDH1A1POLBCYP3A4MAPT | |
| SCHEMBL2118685 | 0.82 | POLB (0.57) | ALDH1A1POLBCYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL2117458 | 0.81 | POLB (0.54) | ALDH1A1POLBMAPTSMN1; SMN2TP53 | |
| SCHEMBL2118988 | 0.81 | TRIM24 (0.56) | TRIM24ALDH1A1POLBCYP3A4MAPT | |
| SCHEMBL2119450 | 0.80 | TRIM24 (0.52) | TRIM24POLBCYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL3792512 | 0.80 | TRIM24 (0.57) | TRIM24ALDH1A1CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | TRIM24 1787/4885ALDH1A1 567/4885POLB 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.