Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185368 | 0.91 | PIK3CD (0.47) | USP2SMN1; SMN2LMNAMAPK1ESR1 | |
| SCHEMBL21185364 | 0.88 | USP2 (0.49) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21028899 | 0.82 | PIK3CD (0.60) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL20081364 | 0.81 | USP2 (0.56) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL16597160 | 0.81 | USP2 (0.56) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL16597180 | 0.81 | USP2 (0.56) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21174774 | 0.79 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CAPIK3R1PIK3CB | |
| SCHEMBL21174771 | 0.79 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CAPIK3R1PIK3CB | |
| SCHEMBL21174818 | 0.79 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3R1PIK3CB | |
| SCHEMBL21174822 | 0.79 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143874-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-07-25 | — | — | WO | disclosed |