Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704094 | 0.91 | PDGFRB (0.53) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL21185438 | 0.88 | PDGFRB (0.51) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL21358445 | 0.79 | PDGFRA (0.58) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL4400367 | 0.78 | PDGFRB (0.72) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL19204448 | 0.78 | PDGFRA (0.48) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL21299301 | 0.72 | PDGFRA (0.50) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL10296329 | 0.72 | PDGFRB (0.55) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL15309998 | 0.71 | SRC (0.53) | PDGFRBPDGFRASRCTGFBR1FGFR2 | |
| SCHEMBL23923068 | 0.70 | PDGFRA (0.69) | PDGFRBPDGFRAFGFR2METAURKA | |
| SCHEMBL7487419 | 0.70 | PDGFRB (0.70) | PDGFRBPDGFRASRCTGFBR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141202-A9 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |
| WO-2019141202-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-07-25 | — | — | WO | disclosed |