Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SCD | O00767 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.44 |
| ▸ | FES | P07332 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186005 | 0.88 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186251 | 0.85 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186158 | 0.83 | SCD (0.51) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186173 | 0.83 | MET (0.51) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186179 | 0.82 | SCD (0.52) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186148 | 0.82 | MAPT (0.46) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186220 | 0.82 | MAPT (0.52) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186137 | 0.81 | MAPK1 (0.48) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186233 | 0.81 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186030 | 0.81 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |