SCHEMBL21186189

SCHEMBL21186189

Cc1ccc(OC(=O)c2ccc3cc(C(=O)Oc4ccc(C)cc4)ccc3c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.61
MEN1 O00255 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
GBA1 P04062 1/20 0.59
ALDH1A1 P00352 2/20 0.57
PRSS1 P07477 1/20 0.57
ACR P10323 1/20 0.57
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
ESR1 P03372 1/20 0.51
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
HGFAC Q04756 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12621712 0.96 KMT2A (0.58) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL12417278 0.95 KMT2A (0.62) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL12734103 0.94 KMT2A (0.56) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL16521504 0.93 KMT2A (0.57) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL14206802 0.93 NPC1 (0.62) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL14996380 0.92 KMT2A (0.63) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL15760481 0.89 KMT2A (0.68) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL12633719 0.89 KMT2A (0.68) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL9663961 0.88 PRSS1 (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL8929987 0.88 PRSS1 (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020121979-A1 LIQUID-CRYSTAL ALIGNMENT AGENT, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-06-18 WO disclosed
WO-2019189632-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
WO-2019189416-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
WO-2019182070-A1 LIQUID CRYSTAL ALIGNING AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
WO-2019142927-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-07-25 WO disclosed