Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186273 | 0.89 | MAPT (0.57) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186117 | 0.89 | MAPT (0.53) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186001 | 0.87 | MAPT (0.67) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186281 | 0.86 | MAPT (0.55) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186252 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186008 | 0.83 | MAPT (0.57) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186278 | 0.82 | MAPT (0.55) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186178 | 0.81 | RAB9A (0.72) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186205 | 0.81 | SCD (0.64) | NPC1RAB9AMAPTSMN1; SMN2HTT | |
| SCHEMBL21186027 | 0.80 | NPC1 (0.62) | NPC1RAB9AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |