Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118552 | 0.90 | FFAR4 (0.51) | PIK3CBALDH1A1KDM4EALPLKIT | |
| SCHEMBL2118551 | 0.83 | PIK3CB (0.50) | PIK3CBALDH1A1KDM4EKITFFAR4 | |
| SCHEMBL2117287 | 0.82 | KDM1A (0.51) | PIK3CBALDH1A1KDM4EALPLKIT | |
| SCHEMBL2118607 | 0.79 | FFAR4 (0.54) | PIK3CBALDH1A1KDM4EKITFFAR4 | |
| SCHEMBL14838614 | 0.78 | FFAR4 (0.70) | ALDH1A1FFAR4MAPTTP53LMNA | |
| SCHEMBL18870862 | 0.76 | FFAR4 (0.67) | ALDH1A1FFAR4MAPTTP53LMNA | |
| SCHEMBL1318958 | 0.76 | KDM4E (0.64) | ALDH1A1KDM4E | |
| SCHEMBL14838612 | 0.75 | FFAR4 (0.66) | ALDH1A1FFAR4MAPTLMNAMEN1 | |
| SCHEMBL2120549 | 0.73 | STAT3 (0.48) | PIK3CBALDH1A1KDM4EALPLKIT | |
| SCHEMBL3367872 | 0.73 | MEN1 (0.73) | ALDH1A1MAPTTP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | PIK3CB 1822/4885ALDH1A1 567/4885KDM4E 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.