Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118551 | 0.96 | PIK3CB (0.50) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2118552 | 0.91 | FFAR4 (0.51) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2120549 | 0.88 | STAT3 (0.48) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2118102 | 0.87 | PIK3CB (0.41) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2116904 | 0.86 | LMNA (0.41) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2120108 | 0.83 | LMNA (0.39) | FFAR4GABRG2GABRB3GABRA3PIK3CB | |
| SCHEMBL2119745 | 0.83 | FFAR4 (0.64) | FFAR4GABRG2GABRB3GABRA3CYP19A1 | |
| SCHEMBL2117686 | 0.81 | FFAR4 (0.61) | FFAR4GABRG2GABRB3GABRA3CYP19A1 | |
| SCHEMBL2118641 | 0.79 | PIK3CB (0.49) | FFAR4PIK3CBKDM4EALDH1A1KIT | |
| SCHEMBL2117823 | 0.78 | PIK3CB (0.52) | FFAR4GABRG2GABRB3GABRA3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | FFAR4 4059/4885GABRG2 4604/4885GABRB3 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.