Sugi Predict

Sugi Predict / Compounds / SCHEMBL21187244

SCHEMBL21187244

SCHEMBL21187244

c1ccc(-c2nc(-c3ccc4oc5ccccc5c4c3)nc(-c3ccc4oc5c(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cccc5c4c3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.45
▸ GGPS1 O95749 1/20 0.37
▸ PRKDC P78527 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ PTGES2 Q9H7Z7 1/20 0.35
▸ SIRT2 Q8IXJ6 1/20 0.35
▸ SIRT1 Q96EB6 1/20 0.35
▸ TSHR P16473 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ CHEK2 O96017 1/20 0.34
▸ PTGER4 P35408 1/20 0.34
▸ PIK3CD O00329 1/20 0.34
▸ PIK3CB P42338 1/20 0.34
▸ PRMT5 O14744 1/20 0.33
▸ WDR77 Q9BQA1 1/20 0.33
▸ PTPRF P10586 2/20 0.33
▸ PTPN2 P17706 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23948026 0.98 ALOX5 (0.43) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL21192031 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL22258073 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL23947804 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL23947811 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL24264258 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL24216818 0.97 ALOX5 (0.40) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL21965108 0.97 ALOX5 (0.46) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL22257609 0.96 ALOX5 (0.40) ALOX5GGPS1PRKDCKDM4EATM
SCHEMBL16582797 0.96 ALOX5 (0.40) ALOX5GGPS1PRKDCKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 — — US disclosed
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 — — US disclosed
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-10-21 — — US disclosed
WO-2019143112-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 2019-07-25 — — WO disclosed
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, UBE2L3, OPRL1 ALOX5 2287/4885GGPS1 1917/4885PRKDC 4727/4885
US-11873297-B2 Compound and organic light emitting device comprising the same CCNL2, UBE2L3, ARL1 ALOX5 2234/4885GGPS1 1969/4885PRKDC 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.