Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158236 | 0.91 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1CDC7CCNT1CSNK2A2 | |
| SCHEMBL24158238 | 0.83 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CDC7CCNT1CSNK2A2 | |
| SCHEMBL24158349 | 0.78 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CHRNA7PTGS1PTGS2 | |
| SCHEMBL22599078 | 0.77 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CDC7CCNT1CSNK2A2 | |
| SCHEMBL21187452 | 0.77 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1CDC7CCNT1CSNK2A2 | |
| SCHEMBL21187470 | 0.68 | PTGS1 (0.40) | HSP90AA1HSP90AB1PTGS1PTGS2DYRK1A | |
| SCHEMBL21187489 | 0.67 | IDO1 (0.41) | HSP90AA1HSP90AB1PTGS1PTGS2DYRK1A | |
| SCHEMBL21187454 | 0.67 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1CDC7CCNT1CSNK2A2 | |
| SCHEMBL21187576 | 0.66 | EGFR (0.39) | HSP90AA1HSP90AB1CTSDBACE1CRHR1 | |
| SCHEMBL24158285 | 0.65 | CLK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740474-B1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2022-01-05 | — | — | EP | disclosed |
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |