SCHEMBL21187694

SCHEMBL21187694

C1CCC2CCCSC2CC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.35
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19415684 1.00 ALDH1A1 (0.37) ALDH1A1MAPK1NOS2
SCHEMBL20254285 1.00 ALDH1A1 (0.37) ALDH1A1MAPK1NOS2
SCHEMBL18685892 1.00 ALDH1A1 (0.37) ALDH1A1MAPK1NOS2
SCHEMBL1255649 0.97 ALDH1A1 (0.39) ALDH1A1MAPK1NOS2
SCHEMBL3070254 0.94 ALDH1A1 (0.37) ALDH1A1MAPK1
SCHEMBL3723527 0.94 ALDH1A1 (0.37) ALDH1A1MAPK1
SCHEMBL21374473 0.94 ALDH1A1 (0.37) ALDH1A1MAPK1
SCHEMBL27805063 0.94 ALDH1A1 (0.37) ALDH1A1MAPK1
SCHEMBL567325 0.94 ALDH1A1 (0.37) ALDH1A1MAPK1
Water SCHEMBL10371455 0.92 ALDH1A1 (0.35) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190228843-A1 Molecule-Based Equation Oriented Reactor Simulation System And Its Model Reduction JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-07-25 US disclosed