Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178725 | 0.91 | POLB (0.67) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL25456568 | 0.91 | POLB (0.67) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL992473 | 0.91 | POLB (0.67) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL16359976 | 0.91 | POLB (0.67) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL3200090 | 0.87 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL5666385 | 0.87 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL1939479 | 0.87 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL15617962 | 0.87 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL3424606 | 0.87 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL16359952 | 0.87 | POLB (0.64) | POLBP2RY2P2RY4P2RY6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790374-B2 | Process for sequence saturation mutagenesis (SeSaM) | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-07 | — | — | US | claimed |
| EP-1670914-B1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AG (DE) | 2008-01-23 | — | — | EP | claimed |
| US-20060223148-A1 | Process for sequence saturation mutagenesis (sesam) | BASF AKTIENGESCHAFT (DE) | 2006-10-05 | — | — | US | claimed |
| EP-1670914-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005035757-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | claimed |
| WO-2014066084-A1 | NUCLEIC ACID MODULATORS OF ALPHA2BETA1 | NOVAMEDICA LIMITED LIABILITY COMPANY (RU) | 2014-05-01 | — | — | WO | disclosed |
| WO-2014066142-A1 | NUCLEIC ACID REGULATION OF GROWTH ARREST-SPECIFIC PROTEIN 6 (GAS6) | NOVAMEDICA LIMITED LIABILITY COMPANY (RU) | 2014-05-01 | — | — | WO | disclosed |
| EP-2627769-A2 | NUCLEIC ACID MODULATORS OF CLEC-2 | Regado Biosciences, Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| US-20120095085-A1 | NUCLEIC ACID MODULATORS OF CLEC-2 | TOBIRA THERAPEUTICS, INC. | 2012-04-19 | — | — | US | disclosed |
| WO-2012051571-A2 | NUCLEIC ACID MODULATORS OF CLEC-2 | REGADO BIOSCIENCES, INC. (US) | 2012-04-19 | — | — | WO | disclosed |
| US-7790374-B2 | Process for sequence saturation mutagenesis (SeSaM) | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-07 | — | — | US | disclosed |
| EP-1670914-B1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-0506242-B1 | Method and compounds for solid phase synthesis of oligonucleotides and oligonucleotide analogs | POLISH ACADEMY OF SCIENCES CEN (PL) | 1998-12-09 | — | — | EP | disclosed |
| EP-0648221-A4 | TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS. | APPLIED BIOSYSTEMS (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0648221-A1 | TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS | THE PERKIN-ELMER CORPORATION (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994000471-A1 | TRITYL MONITOR FOR AUTOMATED POLYNUCLEOTIDE SYNTHESIS | APPLIED BIOSYSTEMS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| EP-0506242-A1 | Method and compounds for solid phase synthesis of oligonucleotides and oligonucleotide analogs | POLISH ACADEMY OF SCIENCES, Center of Molecular and Macromolecular Studies (PL) | 1992-09-30 | — | — | EP | disclosed |
| EP-0439550-A4 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | — | 1991-09-25 | — | — | EP | disclosed |
| EP-0439550-A1 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | DNAX RESEARCH INSTITUTE OF MOLECULAR AND CELLULAR BIOLOGY, INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1990004652-A1 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | DNAX RESEARCH INSTITUTE OF MOLECULAR AND CELLULAR BIOLOGY, INC. (US) | 1990-05-03 | — | — | WO | disclosed |