SCHEMBL992473

SCHEMBL992473

COC[C@H]1O[C@@H](n2ccc(N)nc2=O)C[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.67
P2RY2 P41231 3/20 0.54
P2RY4 P51582 3/20 0.54
P2RY6 Q15077 2/20 0.54
LMNA P02545 3/20 0.49
PDE3A Q14432 3/20 0.49
CACNA1F O60840 2/20 0.49
ALB P02768 2/20 0.49
MAPT P10636 2/20 0.49
CACNA1D Q01668 2/20 0.49
CACNA1S Q13698 2/20 0.49
CACNA1C Q13936 2/20 0.49
ADRB1 P08588 1/20 0.49
DNMT1 P26358 1/20 0.49
THRB P10828 1/20 0.48
MTOR P42345 1/20 0.48
MDM2 Q00987 1/20 0.48
NCOA1 Q15788 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
POLG P54098 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16359976 1.00 POLB (0.67) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL3178725 1.00 POLB (0.67) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL25456568 1.00 POLB (0.67) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL2118780 0.91 POLB (0.64) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL3424606 0.89 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL3200090 0.89 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL1939479 0.89 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL5666385 0.89 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL15617962 0.89 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL1962182 0.89 POLB (0.64) POLBP2RY2P2RY4P2RY6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US claimed
EP-4372091-A2 COMPOSITIONS AND METHODS FOR EDITING NUCLEIC ACIDS IN CELLS UTILIZING OLIGONUCLEOTIDES Woolf, Tod M. (US) 2024-05-22 EP claimed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US claimed
US-11542551-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-01-03 US claimed
US-20200318179-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-10-08 US claimed
CN-106232834-B Sample preparation method 牛津纳米孔技术公司 2020-09-22 CN claimed
US-10669578-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-06-02 US claimed
EP-3108010-B1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECH LTD (GB) 2018-11-28 EP claimed
US-20170067101-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2017-03-09 US claimed
EP-3108010-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2016-12-28 EP claimed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO claimed
WO-2004101822-A2 USE OF BAGE (B MELANOMA ANTIGENS) LOCI AS TUMOUR MARKERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-11-25 WO claimed
US-20260117422-A1 METHODS AND COMPOSITIONS FOR GENOMIC ANALYSIS Twist Bioscience Corporation (US) 2026-04-30 US disclosed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260015392-A1 MUTANT CSGG PORES OXFORD NANOPORE TECHNOLOGIES PLC (BE) 2026-01-15 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
WO-1994005684-A1 N4-METHYL-2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE AND ITS USE IN POLYMERASE-CATALYZED NUCLEIC ACID SYNTHESES LIFE TECHNOLOGIES, INC. (US) 1994-03-17 WO disclosed
EP-0544824-A1 NUCLEASE RESISTANT, PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION. ISIS PHARMACEUTICALS INC (US) 1993-06-09 EP disclosed
WO-1992002258-A1 NUCLEASE RESISTANT, PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1992-02-20 WO disclosed
EP-0450370-A1 Branch migration of nucleotides ENZO BIOCHEM, INC. (US) 1991-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM POLB 4/4885P2RY2 181/4885P2RY4 141/4885
US-20260117422-A1 METHODS AND COMPOSITIONS FOR GENOMIC ANALYSIS DNMT3A, BRCA1, DNMT1 POLB 219/4885P2RY2 1082/4885P2RY4 1019/4885
US-20260015392-A1 MUTANT CSGG PORES NPPA, AFG3L2, SCAMP3 POLB 2723/4885P2RY2 1814/4885P2RY4 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.