⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396456 | 0.79 | — | — | |
| SCHEMBL130245 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL15795891 | 0.76 | NOS3 (0.39) | — | |
| SCHEMBL3655582 | 0.75 | — | — | |
| SCHEMBL21157980 | 0.75 | — | — | |
| SCHEMBL27864887 | 0.75 | — | — | |
| SCHEMBL121166 | 0.75 | — | — | |
| SCHEMBL31181064 | 0.75 | — | — | |
| SCHEMBL26647314 | 0.75 | — | — | |
| SCHEMBL27384724 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930526-A | Preparation method of lebol Lei Sheng intermediate | 东北制药集团股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-118994106-A | Preparation method of diastereoisomer of lebol Lei Sheng | 福安药业集团重庆礼邦药物开发有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-113214164-B | Synthetic method of intermediate 2,4-dimethylpyrimidin-5-ol of Lebo Lei Sheng | 广西天铭药业有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-113214164-A | Synthetic method of Leborane intermediate 2, 4-dimethylpyrimidine-5-ol | 广西天铭药业有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-1006792-B | PROCESS FOR PREPARING HYDROXY, ALKOXYPYRIMIDINE | PFIZER (US) | 1990-02-14 | — | — | CN | claimed |
| CN-121574118-B | Preparation method of lebo Lei Sheng | 湖南迪诺制药股份有限公司 | 2026-05-01 | — | — | CN | disclosed |
| CN-121574118-A | Preparation method of lebo Lei Sheng | 湖南迪诺制药股份有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-20260049069-A1 | METHOD AND COMPOUND USEFUL IN PREPARATION OF OREXIN-2 RECEPTOR ANTAGONIST, AND LEMBOREXANT HAVING FEW IMPURITIES | EISAI R&D MAN CO LTD (JP) | 2026-02-19 | — | — | US | disclosed |
| US-12479819-B2 | Method and compound useful in preparation of orexin-2 receptor antagonist, and lemborexant having few impurities | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-11-25 | — | — | US | disclosed |
| CN-119930526-B | Preparation method of lebol Lei Sheng intermediate | 东北制药集团股份有限公司 | 2025-07-08 | — | — | CN | disclosed |
| CN-119930526-A | Preparation method of lebol Lei Sheng intermediate | 东北制药集团股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930526-A | Preparation method of lebol Lei Sheng intermediate | 东北制药集团股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20080014157-A1 | Skin or hair treatment agents with protective effect | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-17 | — | — | US | disclosed |
| CN-1006792-B | PROCESS FOR PREPARING HYDROXY, ALKOXYPYRIMIDINE | PFIZER (US) | 1990-02-14 | — | — | CN | disclosed |
| CN-86104539-A | Hydroxyl and alkoxyl group miazines | — | 1987-01-21 | — | — | CN | disclosed |