Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189366 | 0.86 | CHRM3 (0.39) | CHRM3MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21189406 | 0.86 | CHRM2 (0.41) | CHRM3TRPV1TP53 | |
| SCHEMBL21189255 | 0.86 | TRPV1 (0.40) | TRPV1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL21189435 | 0.86 | TRPV1 (0.40) | TRPV1NPC1RAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL19973591 | 0.86 | CHRM2 (0.40) | CHRM3TRPV1TP53 | |
| SCHEMBL21189274 | 0.85 | CHRNB2 (0.38) | CHRM3TRPV1 | |
| SCHEMBL21189209 | 0.85 | CHRM3 (0.41) | CHRM3TRPV1 | |
| SCHEMBL21189519 | 0.84 | TP53 (0.38) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21189357 | 0.84 | TP53 (0.38) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21189326 | 0.84 | NPC1 (0.45) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001564-B2 | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-05-11 | — | — | US | disclosed |
| US-20190225593-A1 | SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225593-A1 | SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME | CBX8, HAVCR2, HCCS | CHRM3 2581/4885MAPT 3165/4885TRPV1 3647/4885 |
| US-11001564-B2 | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same | CBX8, HAVCR2, HCCS | CHRM3 2581/4885MAPT 3165/4885TRPV1 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.