Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189441 | 0.93 | PDK1 (0.34) | PDK1MCL1KIF18ANMT1 | |
| SCHEMBL30391515 | 0.93 | PDK1 (0.34) | PDK1MCL1KIF18ANMT1 | |
| SCHEMBL21189604 | 0.90 | PDK1 (0.35) | PDK1MCL1KIF18AFFAR1NMT1 | |
| SCHEMBL21189495 | 0.89 | PDK1 (0.34) | PDK1MCL1FFAR1NMT1 | |
| SCHEMBL21189623 | 0.88 | PDK1 (0.34) | PDK1MCL1FFAR1 | |
| SCHEMBL21189836 | 0.87 | PDK1 (0.34) | PDK1MCL1KIF18AFFAR1 | |
| SCHEMBL30391724 | 0.83 | PDK1 (0.35) | PDK1MCL1KIF18AFFAR1NMT1 | |
| SCHEMBL21189605 | 0.83 | PDK1 (0.35) | PDK1MCL1KIF18AFFAR1NMT1 | |
| SCHEMBL21177211 | 0.82 | PDK1 (0.41) | PDK1KIF18AFFAR1NMT1F2 | |
| SCHEMBL21189738 | 0.82 | PDK1 (0.34) | PDK1MCL1NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141694-A1 | PI4KIIIBETA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-25 | — | — | WO | disclosed |