Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SNCA | P37840 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005063 | 0.83 | SNCA (0.65) | MAPTSNCAPOLBKDM4EKMT2A | |
| SCHEMBL19995103 | 0.83 | MAPT (0.56) | MAPTSNCAPOLBKDM4EKMT2A | |
| SCHEMBL20004978 | 0.72 | SNCA (1.00) | MAPTSNCA | |
| SCHEMBL21115115 | 0.70 | RORC (0.46) | MAPTPOLBKMT2ANR1H2NR1I2 | |
| SCHEMBL22537776 | 0.69 | SNCA (0.59) | MAPTSNCA | |
| SCHEMBL20005056 | 0.64 | SNCA (0.69) | MAPTSNCA | |
| SCHEMBL20005022 | 0.63 | NR1I2 (0.55) | MAPTPOLBKDM4EKMT2ANR1I2 | |
| SCHEMBL9737942 | 0.63 | NAMPT (0.54) | NAMPT | |
| SCHEMBL20004999 | 0.62 | SNCA (1.00) | MAPTSNCA | |
| SCHEMBL20004553 | 0.61 | SNCA (1.00) | MAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | Centre National De La Recherche Scientifique (FR) | 2019-07-31 | — | — | EP | disclosed |