SCHEMBL21195752

SCHEMBL21195752

C=CCO[C@H]1O[C@@H]2COC(c3ccccc3)O[C@H]2[C@@H](OS(=O)(=O)C(F)(F)F)[C@H]1NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ SELP P16109 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21195685 1.00 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1SELP
SCHEMBL29137572 0.85 KMT2A (0.48) L3MBTL1KMT2AMEN1SELP
SCHEMBL21195696 0.85 KMT2A (0.48) L3MBTL1KMT2AMEN1SELP
SCHEMBL21195676 0.85 KMT2A (0.48) L3MBTL1KMT2AMEN1SELP
SCHEMBL29137571 0.84 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1SELP
SCHEMBL21195695 0.80 L3MBTL1 (0.42) L3MBTL1KMT2AMEN1
SCHEMBL1673967 0.77 L3MBTL1 (0.63) L3MBTL1KMT2AMEN1SELP
SCHEMBL14206021 0.76 L3MBTL1 (0.56) L3MBTL1KMT2AMEN1SELP
SCHEMBL13262234 0.76 KMT2A (0.53) L3MBTL1KMT2AMEN1SELP
SCHEMBL2794837 0.76 L3MBTL1 (0.58) L3MBTL1KMT2AMEN1SELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851130-B2 Chemical synthesis method of Plesiomonas shigelloides serotype O51 O-antigen oligosaccharide JIANGNAN UNIVERSITY (CN) 2020-12-01 — — US disclosed
US-20190233459-A1 Chemical Synthesis Method of Plesiomonas Shigelloides Serotype O51 O-antigen Oligosaccharide JIANGNAN UNIVERSITY (CN) 2019-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190233459-A1 Chemical Synthesis Method of Plesiomonas Shigelloides Serotype O51 O-antigen Oligosaccharide DDOST, OSTC, OGA L3MBTL1 3196/4885KMT2A 3470/4885MEN1 4394/4885
US-10851130-B2 Chemical synthesis method of Plesiomonas shigelloides serotype O51 O-antigen oligosaccharide DDOST, OSTC, OGA L3MBTL1 3196/4885KMT2A 3470/4885MEN1 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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