⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330882 | 1.00 | — | — | |
| SCHEMBL2120089 | 1.00 | — | — | |
| SCHEMBL28988498 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL2122173 | 0.77 | — | — | |
| SCHEMBL2122168 | 0.77 | — | — | |
| SCHEMBL8872890 | 0.75 | — | — | |
| SCHEMBL107864 | 0.73 | — | — | |
| SCHEMBL1760782 | 0.73 | — | — | |
| SCHEMBL107863 | 0.73 | — | — | |
| SCHEMBL1586682 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143757-B | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4393907-A1 | POTASSIUM CHANNEL MODULATOR, COMPOSITION AND APPLICATION | Neushen Therapeutics (Shanghai) Co., Ltd (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4342892-A1 | BRUTON'S TYROSINE KINASE AND MUTANT DEGRADER, COMPOSITION AND APPLICATION THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2024-03-27 | — | — | EP | disclosed |
| US-20230250218-A1 | URETHANE COMPOSITION | NITTO KASEI CO., LTD. (JP) | 2023-08-10 | — | — | US | disclosed |
| EP-4198068-A1 | URETHANE COMPOSITION | Nitto Kasei Co., Ltd. (JP) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| CN-116217566-A | Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2023088477-A1 | MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE | 杭州和正医药有限公司 | 2023-05-25 | — | — | WO | disclosed |
| CN-116143757-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116018365-A | Carbamate composition | 日东化成株式会社 | 2023-04-25 | — | — | CN | disclosed |
| EP-0589313-A1 | Cyclohex(en)ylcarboxamides, process for their preparation and anti-fungal agents containing them | BASF Aktiengesellschaft (DE) | 1994-03-30 | — | — | EP | disclosed |
| CN-1064683-A | New beta-amino-alpha-hydroxycarboxylic acids and uses thereof | SANKYO CO (JP) | 1992-09-23 | — | — | CN | disclosed |
| EP-0498680-A1 | New beta-amino-alpha-hydroxycarboxylic acids and their use | Sankyo Company Limited (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-4914116-A | Nitrogen-containing heterocyclic compounds, and their use as insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4847259-A | Nitrogen-containing heterocyclic compounds, and use as insecticide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4755598-A | 1'-(substituted)ethyl-7β-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]methyl]ceph-3-em-4-carboxylate derivatives having antibacterial utility | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-07-05 | — | — | US | disclosed |
| US-4714706-A | JUVENILE HORMONE INHIBITORS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0203798-A2 | Nitrogen-containing heterocyclic compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0128028-A2 | Cephalosporin derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |